Mark R. Mandel, MD

Mark R. Mandel, MD has been selected by hundreds of eye doctors and other physicians to perform LASIK, corneal transplant, and cataract surgery on themselves, their families, and their office staff.

Mark R. Mandel, MD

As a sub-specialist Dr. Mandel has performed over 70,000 LASIK procedures and 20,000 cataract/IOL procedures. He has been serving Bay Area patients since 1983.

Mark R. Mandel, MD

We are proud to offer state of the art technology for measuring the eye and performing the latest in advanced surgical techniques… always striving to achieve the best possible outcomes.

Mark R. Mandel, MD

Graduate of Oxford University, UCLA School of Medicine, Fellowship trained cornea transplant and refractive specialist. Chosen by more surgeons to perform surgery on themselves and their families.


Large Pupil Complications in Refractive Surgery Patients

The Large Pupil in the Refractive Surgery Patient

Mark Mandel, MD has been performing LASIK surgery and advanced surface procedures on patients with pupils up to 9mm using either the Allegretto laser or the VISX Star S4 with the large pupil software and/or wavefront guided treatment for 25 years.

There are a number of complex optical reasons why patients experience post-operative halos, glare, and starbursts, including the induction of higher order aberrations such as spherical aberration, coma, and trefoil, as well as diffraction off the edge of the treatment zone in patients with large pupils, made worse by an excessively flat corneal curvature after surgery.

In some patients, the pupils can dilate in the dark to as large as 8-9mm in diameter. Generally, this is not a problem. However, following refractive surgery, the pupil may dilate wider than the zone of treatment, thereby causing reflection and diffraction of incoming light off the edge of the treatment zone. This diffraction can degrade the quality of the image (experienced as decreased contrast sensitivity or a decreased ability to discern subtle shades of gray), or cause halos/starbursts off of point sources of light. This is more common in patients with higher degrees of astigmatism and a “flatter” corneal curvature because of the configuration of the treatment zone.

We have been performing LASIK and advanced surface procedures on patients with pupils up to 9mm using either the Allegretto laser or the VISX Star S4 with the large pupil software and/or wavefront guided treatment. Although patients with large pupils still experience glare and halos similar to that with their pre-operative contact lenses or glasses, we have had very few cases of worsening glare or halos in patients with large pupils.

In addition to being able to accommodate patients with very large pupils, the Allegretto and the VISX S4 excimer lasers use an active tracking mechanism whereby the patient’s eye is tracked by the laser which essentially eliminates problems associated with slight movement of the eye during the surgery.

Please consult our website page on surface PRK versus LASEK versus LASIK, and the section on LASEK for further details on these procedures.

The Triad of Large Pupil, High Myopia/Astigmatism, and Corneal Thickness – LASIK versus PRK

Unfortunately, not all patients with large pupils are good candidates for LASIK using the large pupil laser. This is because as we increase the size of the treatment zone necessary for accommodating patients with large pupils, the laser must remove more corneal tissue. It is wise to leave approximately 250 microns of cornea untreated by the excimer laser. Accordingly, in patients with large pupils who require not only large treatment areas, but deep treatment, the patient’s cornea must be thick enough to leave approximately 250 microns untouched.

At the pre-operative examination we measure the patient’s corneal thickness and calculate the treatment zone size and depth. In some cases in patients who are highly nearsighted and have large pupils, but do not have enough corneal thickness to leave the approximate 250 microns of untouched cornea, it is not possible to safely perform a LASIK. In these cases, assuming that the cornea is otherwise healthy, a surface PRK procedure can be performed. Please consult our web site page on Surface PRK versus LASIK, and the section on PRK for further details on these procedures.

It is important to emphasize that although LASIK is more convenient for the patient with respect to the fact that the visual recovery time is rapid, PRK have the same visual results, but take longer to achieve the crispness of vision enjoyed by LASIK patients. On the other hand, one of the main complications of LASIK in the highly nearsighted individual is microfolds in the flap which tend to be more common in patients with 6.00 diopters of nearsightedness and above. Because PRK does not use a flap, it is impossible to have the complication of microfolds. We believe that this is a significant advantage. However, the risk of corneal haze and scarring is slightly greater in the high myope with the PRK procedure. Fortunately, with the newer generation lasers such as the Allegretto laser and the VISX S4 Smooth Scan laser, and the use of intra-operative Mitomicin-C the risk of corneal scarring and haze following PRK is considerably less than it was years ago. Therefore, in the patient with a large pupil, high myopia, and a thin cornea, we are fortunate that we have the Allegretto large pupil laser and PRK at our disposal.

If the patient elects to have PRK, they must decide whether to do one eye at a time or both eyes at the same time. The advantage of doing both eyes at the same time is that the patient does not have to return to the laser center on two occasions. However, it is important to note that, depending on the size of the treatment area, it may take 30 days for the vision to become sharp enough to function at work. Accordingly, patients who will undergo PRK may elect to have one eye done at a time while wearing a contact lens or glasses over the eye that has not been treated. Once the treated eye has achieved functional vision, then the PRK procedure can be performed in the second eye.

Please feel free to call 510.886.3937 ext. 3 or 877.210.2020 ext. 3

Sarah Lee shares her successful LASIK experience. Click below to enjoy her video.

Physicians and patients have traveled from all over the world to Mark R. Mandel, MD

If you would like to meet with Dr. Mandel to discuss your personal vision needs, please contact our office today to schedule a consultation.

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Laser Refractive Surgeries

Laser refractive surgery corrects focusing errors of the eye (e.g., nearsightedness, farsightedness, astigmatism) in order to improve visual sharpness and clarity. Procedures include LASIK, laser cataract surgery and refractive lens exchange.


Premium Cataract Surgery

At Optima Eye we offer premium cataract surgery. Patients can opt for laser cataract surgery and / or premium intraocular lens implants, with several options to fit your unique lifestyle.


Complete Eye Care

Dr. Mandel and his team of professionals offer a complete continuum of general eye care services to accommodate every patient’s needs — whether those needs are as simple as a routine eye exam, or as complex as laser vision correction.


Dry Eye Treatment

Dry eye syndrome, which affects more than 100 million people worldwide, can be painful and debilitating. Dr. Mandel uses several approaches to treat dry eye, ranging from medication to punctal plugs.


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Hayward Location

1237 B Street
Hayward, CA 94541

San Jose Location

455 O’Connor Drive, Suite 360
San Jose, CA 95128

Castro Valley Location

20400 Lake Chabot Road, Suite 302
Castro Valley, CA 94546

Concord Location

1401 Willow Pass Rd., Suite 100
Concord, CA 94520
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